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Small Business Grants in Colorado

Colorado has built one of the most vibrant entrepreneurial ecosystems in the country, combining a highly educated workforce, strong quality of life, and proactive government support for small businesses. The state regularly ranks among the top destinations for startup founders, remote workers, and small business owners. From the tech and aerospace corridors along the Front Range to the tourism-driven mountain communities and agricultural operations on the Eastern Plains, Colorado offers diverse funding opportunities for businesses of every size and type.

Economic Overview

Colorado's economy is driven by technology, aerospace and defense, renewable energy, outdoor recreation, agriculture, cannabis, and tourism. The state has approximately 670,000 small businesses employing over 1.1 million workers. Colorado consistently ranks in the top 10 states for business formation per capita, and the Denver-Boulder metro area is one of the nation's leading startup ecosystems. The state has a flat income tax rate, no inventory tax, and significant incentives for businesses in targeted industries. Colorado's SBDC network, run through the Office of Economic Development and International Trade (OEDIT), is highly active and well-funded.

State Grant Programs

OEDIT administers several programs relevant to small businesses, including the Advanced Industries Accelerator Grant Program, which provides proof-of-concept and early-stage capital grants to businesses in seven designated advanced industries (aerospace, bioscience, electronics, energy, infrastructure engineering, materials science, and technology). The Colorado Enterprise Fund offers microloans and small business loans to underserved entrepreneurs. The state's Rural Jump-Start Program provides tax incentives for new businesses in rural counties. The Energize Colorado Gap Fund distributed millions in grants and loans to small businesses and may have ongoing successor programs. Boulder, Denver, and Fort Collins all run active local grant and incentive programs.

How to Apply

Visit the OEDIT website and the Colorado SBDC for comprehensive guidance. If your business has a technology or innovation component, the Advanced Industries program should be your top priority — it is one of the best state-level grant programs in the country. Register with SAM.gov for federal grants. For rural Colorado businesses, contact the USDA Colorado office and explore the Rural Jump-Start Program. The Denver Metro SBDC and Boulder SBDC are particularly well-connected to the startup ecosystem.

Featured Opportunities66 Active

OEDITTechnology

Award Amount

$50,000 - $150,000

Colorado Advanced Industries Proof of Concept Grant

Statewide, CO
Closes: Varies
OEDITTechnology

Award Amount

$50,000 - $250,000

Colorado Early-Stage Capital & Retention Grant

Statewide, CO
Closes: Varies
OEDITTechnology

Award Amount

$5,000 - $15,000

Colorado Advanced Industries Export Grant

Statewide, CO
Closes: Rolling
National Association for the Self-EmployedSmall Business

Award Amount

$4,000 - $4,000

NASE Growth Grant

National, US
Closes: Rolling
WomensNetSmall Business

Award Amount

$10,000 - $50,000

Amber Grant for Women

National, US
Closes: Monthly
National Science FoundationTechnology

Award Amount

$275,000 - $305,000

NSF SBIR Phase I (America's Seed Fund)

National, US
Closes: Rolling
USDA Rural DevelopmentAgriculture

Award Amount

$10,000 - $500,000

USDA Rural Business Development Grants

National, US
Closes: Rolling
SkipSmall Business

Award Amount

$1,000 - $10,000

Skip Monthly Business Grants

National, US
Closes: Monthly
IFundWomenSmall Business

Award Amount

$5,000 - $25,000

IFundWomen Universal Grant Application

National, US
Closes: Rolling
VerizonSmall Business

Award Amount

$10,000 - $10,000

Verizon Small Business Digital Ready

National, US
Closes: Rolling
PayPal / VenmoSmall Business

Award Amount

$10,000 - $10,000

Venmo Small Business Grant

National, US
Closes: Varies
Department of DefenseTechnology

Award Amount

$50,000 - $275,000

DOD SBIR Phase I

National, US
Closes: Rolling
National Institutes of HealthHealthcare

Award Amount

$150,000 - $293,297

NIH SBIR/STTR Phase I

National, US
Closes: Varies
Department of EnergyTechnology

Award Amount

$50,000 - $200,000

DOE SBIR/STTR Phase I

National, US
Closes: Varies
NASATechnology

Award Amount

$150,000 - $750,000

NASA SBIR/STTR

National, US
Closes: Varies
USDA NIFAAgriculture

Award Amount

$50,000 - $150,000

USDA SBIR Phase I

National, US
Closes: Varies
Environmental Protection AgencyTechnology

Award Amount

$50,000 - $100,000

EPA SBIR Phase I

National, US
Closes: Varies
USDA Rural DevelopmentAgriculture

Award Amount

$75,000 - $750,000

USDA Value-Added Producer Grant

National, US
Closes: 2026-04-22
USDA Rural DevelopmentAgriculture

Award Amount

$2,500 - $1,000,000

USDA Rural Energy for America (REAP)

National, US
Closes: Rolling
Economic Development AdministrationSmall Business

Award Amount

$600,000 - $5,000,000

EDA Public Works Program

National, US
Closes: Rolling
Economic Development AdministrationSmall Business

Award Amount

$150,000 - $2,500,000

EDA Economic Adjustment Assistance

National, US
Closes: Rolling
Economic Development AdministrationTechnology

Award Amount

$250,000 - $2,000,000

EDA Build to Scale (Venture Challenge)

National, US
Closes: Varies
Small Business AdministrationSmall Business

Award Amount

$75,000 - $150,000

SBA Growth Accelerator Fund Competition

National, US
Closes: Varies
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA HUBZone Program

National, US
Closes: Rolling
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA 8(a) Business Development Program

National, US
Closes: Rolling
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA Women-Owned Small Business Contracting

National, US
Closes: Rolling
Hello AliceSmall Business

Award Amount

$5,000 - $25,000

Hello Alice Small Business Growth Fund

National, US
Closes: Rolling
Hello Alice / AllstateSmall Business

Award Amount

$20,000 - $20,000

Allstate Main Street Grants (Hello Alice)

National, US
Closes: Rolling
Hello Alice / H&R BlockSmall Business

Award Amount

$10,000 - $50,000

Fund Her Future Grant (H&R Block)

National, US
Closes: Varies
KivaSmall Business

Award Amount

$1,000 - $15,000

Kiva 0% Interest Microloans

National, US
Closes: Rolling
FedExSmall Business

Award Amount

$10,000 - $10,000

FedEx Amplify Growth Lab

National, US
Closes: Varies
FedExSmall Business

Award Amount

$10,000 - $10,000

FedEx Boost Camp

National, US
Closes: Varies
Amazon BusinessSmall Business

Award Amount

$15,000 - $25,000

Amazon Business Small Business Grant

National, US
Closes: Varies
GoogleTechnology

Award Amount

$2,000 - $350,000

Google for Startups Cloud Program

National, US
Closes: Rolling
VisaTechnology

Award Amount

$20,000 - $100,000

Visa Everywhere Initiative

National, US
Closes: Varies
ComcastSmall Business

Award Amount

$5,000 - $10,000

Comcast RISE

National, US
Closes: Varies
Intuit QuickBooksSmall Business

Award Amount

$20,000 - $20,000

Intuit QuickBooks Small Business Hero

National, US
Closes: 2026-05-15
Ladies Who LaunchSmall Business

Award Amount

$10,000 - $10,000

Ladies Who Launch Program

National, US
Closes: Varies
Freed FellowshipSmall Business

Award Amount

$500 - $2,500

Freed Fellowship Grant

National, US
Closes: Monthly
eBaySmall Business

Award Amount

$10,000 - $10,000

eBay Up & Running Grants

National, US
Closes: Varies
NavSmall Business

Award Amount

$5,000 - $10,000

Nav Small Business Grants

National, US
Closes: Quarterly
MassChallengeTechnology

Award Amount

$25,000 - $100,000

MassChallenge Accelerator (Equity-Free)

National, US
Closes: Varies
Southern Smoke FoundationRestaurant

Award Amount

$1,000 - $5,000

Southern Smoke Emergency Relief Fund

National, US
Closes: Rolling
CartierSmall Business

Award Amount

$30,000 - $100,000

Cartier Women's Initiative (2027 Cycle)

National, US
Closes: 2026-06-16
Boundless Futures FoundationSmall Business

Award Amount

$10,000 - $50,000

EmpowHer Grant

National, US
Closes: 2026-06-01
Halstead BeadSmall Business

Award Amount

$7,500 - $7,500

Halstead Grant for Jewelry Designers

National, US
Closes: 2026-05-01
Girlboss FoundationSmall Business

Award Amount

$15,000 - $15,000

Girlboss Foundation Grant

National, US
Closes: Varies
Spanx by Sara Blakely FoundationSmall Business

Award Amount

$5,000 - $5,000

Red Backpack Fund (Spanx Foundation)

National, US
Closes: Monthly
Tory Burch FoundationSmall Business

Award Amount

$5,000 - $5,000

Tory Burch Foundation Fellows

National, US
Closes: Varies
National Association of Women Business Owners / MastercardSmall Business

Award Amount

$10,000 - $10,000

NAWBO / Mastercard Small Business Grants

National, US
Closes: Varies
Second Service FoundationSmall Business

Award Amount

$2,000 - $5,000

Second Service Foundation Veteran Awards

National, US
Closes: Monthly
U.S. Chamber of Commerce FoundationSmall Business

Award Amount

$10,000 - $25,000

Hiring Our Heroes Small Business Grant

National, US
Closes: Varies
PenFed FoundationSmall Business

Award Amount

$5,000 - $50,000

PenFed Foundation Veteran Entrepreneur Program

National, US
Closes: Rolling
NAACPSmall Business

Award Amount

$25,000 - $25,000

NAACP Powershift Entrepreneur Grant

National, US
Closes: Varies
NAACP / L'OrealSmall Business

Award Amount

$25,000 - $25,000

NAACP x L'Oreal Beauty Industry Grants

National, US
Closes: 2026-04-23
Fearless Fund / MastercardSmall Business

Award Amount

$10,000 - $20,000

Fearless Strivers Grant (Fearless Fund + Mastercard)

National, US
Closes: Rolling
First Nations Development InstituteSmall Business

Award Amount

$1,500 - $5,000

First Nations Acorn Fund

National, US
Closes: 2026-04-29
First Nations Development InstituteAgriculture

Award Amount

$10,000 - $40,000

First Nations Native Food Sovereignty Grant

National, US
Closes: Varies
National Black MBA AssociationSmall Business

Award Amount

$10,000 - $50,000

NBMBAA Scale-Up Pitch Challenge

National, US
Closes: Varies
SoGal FoundationTechnology

Award Amount

$5,000 - $10,000

SoGal Foundation Black Founder Grant

National, US
Closes: Rolling
DigitalUndivided / JPMorgan ChaseTechnology

Award Amount

$5,000 - $5,000

DigitalUndivided Breakthrough Program

National, US
Closes: Varies
National Disability Institute / Verizon / SBASmall Business

Award Amount

$5,000 - $10,000

NDI Small Business Hub (Disability Entrepreneurs)

National, US
Closes: Rolling
NAACP / BACARDIRestaurant

Award Amount

$5,000 - $25,000

NAACP x BACARDI Backing the B.A.R.

National, US
Closes: Varies
NAACP / Vistaprint / Boston CelticsSmall Business

Award Amount

$25,000 - $25,000

NAACP Power Forward Small Business Grant

National, US
Closes: Rolling
MetaTechnology

Award Amount

$25,000 - $200,000

Meta AI Glasses Impact Grants

National, US
Closes: Varies
U.S. Hispanic Chamber of Commerce / Wells FargoSmall Business

Award Amount

$5,000 - $15,000

USHCC / Wells Fargo Hispanic Business Grants

National, US
Closes: Varies

Frequently Asked Questions

What grants are available for Colorado small businesses?

Colorado offers the Advanced Industries Accelerator Grant, various programs through OEDIT, the Colorado Enterprise Fund, Rural Jump-Start incentives, and federal programs like SBIR/STTR. Denver, Boulder, and other cities also run local business grant programs periodically.

What is the Advanced Industries Accelerator Grant?

This is a Colorado state grant program providing early-stage capital to companies in seven advanced industries: aerospace, bioscience, electronics, energy, infrastructure engineering, materials science, and technology. Grants support proof-of-concept research and early-stage capital needs.

Are there grants for rural Colorado businesses?

Yes. The Rural Jump-Start Program provides significant tax incentives for new businesses in eligible rural counties. USDA Rural Development grants are also widely available. The Colorado Enterprise Fund specifically targets underserved communities including rural areas.

Don't see a perfect match?

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