Small Business Grants in Missouri
Missouri sits at the geographic center of the US and offers small businesses access to two major metros (Kansas City and St. Louis), a diverse economy, and competitive operating costs. The state has a long history of entrepreneurship and innovation — it's home to major companies like Cerner, Emerson Electric, and World Wide Technology — and has invested in programs to support the next generation of small businesses.
Economic Overview
Missouri has approximately 540,000 small businesses employing over 1.1 million workers. The economy spans advanced manufacturing, agriculture, financial services, healthcare, technology, and logistics. Both Kansas City and St. Louis have active startup ecosystems with growing venture capital activity. Missouri's central location provides logistics advantages, and the cost of living is below the national average in most areas.
State Grant Programs
The Missouri Department of Economic Development offers the Missouri Works Program (tax credits for job creation), the BUILD Missouri Program, and various workforce training incentives. The Missouri Technology Corporation (MTC) provides venture capital and grants to tech startups through the IDEA Fund. The Missouri SBDC has offices across the state. Kansas City's LaunchKC offers grants to startups relocating to KC. The Cortex Innovation Community in St. Louis is a major tech hub.
How to Apply
Visit the Missouri DED website and contact the Missouri SBDC. Tech startups should explore MTC's IDEA Fund. In Kansas City, check LaunchKC and the KC Startup Foundation. In St. Louis, connect with Cortex, T-REX, and Arch Grants (which gives $50K equity-free grants to startups). Register at SAM.gov for federal grants.
Featured Opportunities63 Active
Award Amount
$4,000 - $4,000
NASE Growth Grant
Award Amount
$10,000 - $50,000
Amber Grant for Women
Award Amount
$275,000 - $305,000
NSF SBIR Phase I (America's Seed Fund)
Award Amount
$10,000 - $500,000
USDA Rural Business Development Grants
Award Amount
$1,000 - $10,000
Skip Monthly Business Grants
Award Amount
$5,000 - $25,000
IFundWomen Universal Grant Application
Award Amount
$10,000 - $10,000
Verizon Small Business Digital Ready
Award Amount
$10,000 - $10,000
Venmo Small Business Grant
Award Amount
$50,000 - $275,000
DOD SBIR Phase I
Award Amount
$150,000 - $293,297
NIH SBIR/STTR Phase I
Award Amount
$50,000 - $200,000
DOE SBIR/STTR Phase I
Award Amount
$50,000 - $100,000
EPA SBIR Phase I
Award Amount
$75,000 - $750,000
USDA Value-Added Producer Grant
Award Amount
$2,500 - $1,000,000
USDA Rural Energy for America (REAP)
Award Amount
$600,000 - $5,000,000
EDA Public Works Program
Award Amount
$150,000 - $2,500,000
EDA Economic Adjustment Assistance
Award Amount
$250,000 - $2,000,000
EDA Build to Scale (Venture Challenge)
Award Amount
$75,000 - $150,000
SBA Growth Accelerator Fund Competition
Award Amount
$50,000 - $4,500,000
SBA HUBZone Program
Award Amount
$50,000 - $4,500,000
SBA 8(a) Business Development Program
Award Amount
$50,000 - $4,500,000
SBA Women-Owned Small Business Contracting
Award Amount
$5,000 - $25,000
Hello Alice Small Business Growth Fund
Award Amount
$20,000 - $20,000
Allstate Main Street Grants (Hello Alice)
Award Amount
$10,000 - $50,000
Fund Her Future Grant (H&R Block)
Award Amount
$1,000 - $15,000
Kiva 0% Interest Microloans
Award Amount
$15,000 - $25,000
Amazon Business Small Business Grant
Award Amount
$2,000 - $350,000
Google for Startups Cloud Program
Award Amount
$20,000 - $20,000
Intuit QuickBooks Small Business Hero
Award Amount
$10,000 - $10,000
Ladies Who Launch Program
Award Amount
$500 - $2,500
Freed Fellowship Grant
Award Amount
$25,000 - $100,000
MassChallenge Accelerator (Equity-Free)
Award Amount
$1,000 - $5,000
Southern Smoke Emergency Relief Fund
Award Amount
$30,000 - $100,000
Cartier Women's Initiative (2027 Cycle)
Award Amount
$10,000 - $50,000
EmpowHer Grant
Award Amount
$7,500 - $7,500
Halstead Grant for Jewelry Designers
Award Amount
$15,000 - $15,000
Girlboss Foundation Grant
Award Amount
$5,000 - $5,000
Red Backpack Fund (Spanx Foundation)
Award Amount
$5,000 - $5,000
Tory Burch Foundation Fellows
Award Amount
$10,000 - $10,000
NAWBO / Mastercard Small Business Grants
Award Amount
$2,000 - $5,000
Second Service Foundation Veteran Awards
Award Amount
$10,000 - $25,000
Hiring Our Heroes Small Business Grant
Award Amount
$5,000 - $50,000
PenFed Foundation Veteran Entrepreneur Program
Award Amount
$25,000 - $25,000
NAACP Powershift Entrepreneur Grant
Award Amount
$25,000 - $25,000
NAACP x L'Oreal Beauty Industry Grants
Award Amount
$10,000 - $20,000
Fearless Strivers Grant (Fearless Fund + Mastercard)
Award Amount
$1,500 - $5,000
First Nations Acorn Fund
Award Amount
$10,000 - $40,000
First Nations Native Food Sovereignty Grant
Award Amount
$10,000 - $50,000
NBMBAA Scale-Up Pitch Challenge
Award Amount
$5,000 - $10,000
SoGal Foundation Black Founder Grant
Award Amount
$5,000 - $5,000
DigitalUndivided Breakthrough Program
Award Amount
$5,000 - $10,000
NDI Small Business Hub (Disability Entrepreneurs)
Award Amount
$5,000 - $25,000
NAACP x BACARDI Backing the B.A.R.
Award Amount
$25,000 - $25,000
NAACP Power Forward Small Business Grant
Award Amount
$5,000 - $15,000
USHCC / Wells Fargo Hispanic Business Grants
Frequently Asked Questions
What grants are available for Missouri small businesses?▼
Missouri offers Missouri Works tax credits, MTC IDEA Fund for tech startups, Arch Grants ($50K equity-free in St. Louis), LaunchKC grants in Kansas City, BUILD Missouri, and federal SBIR/STTR and USDA programs.
Grants by Group in Missouri
Grants by Industry in Missouri
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