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Small Business Grants for Healthcare & Biotech (2026)

Healthcare and biotech startups have access to some of the largest grant programs in the federal government, led by the National Institutes of Health SBIR/STTR program which funds hundreds of small businesses each year developing medical devices, therapeutics, diagnostics, and health IT solutions.

NIH SBIR Phase I awards up to $293,297 for feasibility studies, with Phase II funding up to $1,955,314 for continued development. The program covers virtually every area of biomedical research, from cancer therapeutics and rare disease treatments to digital health platforms and medical imaging technology.

Beyond NIH, the Department of Defense funds healthcare innovations relevant to military medicine, the Department of Energy supports bioenergy research, and the EPA funds environmental health technologies. The NSF also funds health-adjacent technologies in areas like biomedical engineering and computational biology.

State-level programs provide additional support. Maryland's TEDCO invests in early-stage biotech companies. Pennsylvania's Ben Franklin Technology Partners funds healthcare innovators across the state. Colorado's Advanced Industries program includes bioscience as a priority sector.

Private and corporate programs round out the landscape. MassChallenge runs health-focused accelerator tracks. Google for Startups supports health AI companies. Various disease-specific foundations offer grants for companies developing treatments in their focus areas.

The healthcare grant ecosystem rewards companies with strong scientific evidence, clear regulatory pathways, and the potential to meaningfully improve patient outcomes. Companies with academic partnerships, preliminary data, and experienced management teams tend to be the most competitive applicants.

Active Healthcare & Biotech Grants75 Available

National Institutes of HealthHealthcare

Award Amount

$150,000 - $293,297

NIH SBIR/STTR Phase I

National, US
Closes: Varies
National Association for the Self-EmployedSmall Business

Award Amount

$4,000 - $4,000

NASE Growth Grant

National, US
Closes: Rolling
WomensNetSmall Business

Award Amount

$10,000 - $50,000

Amber Grant for Women

National, US
Closes: Monthly
SkipSmall Business

Award Amount

$1,000 - $10,000

Skip Monthly Business Grants

National, US
Closes: Monthly
IFundWomenSmall Business

Award Amount

$5,000 - $25,000

IFundWomen Universal Grant Application

National, US
Closes: Rolling
VerizonSmall Business

Award Amount

$10,000 - $10,000

Verizon Small Business Digital Ready

National, US
Closes: Rolling
PayPal / VenmoSmall Business

Award Amount

$10,000 - $10,000

Venmo Small Business Grant

National, US
Closes: Varies
California Office of the Small Business AdvocateSmall Business

Award Amount

$10,000 - $10,000

California Dream Fund

Statewide, CA
Closes: Varies
Office of the Texas GovernorSmall Business

Award Amount

$10,000 - $1,000,000

Texas Enterprise Fund

Statewide, TX
Closes: Rolling
Empire State DevelopmentSmall Business

Award Amount

$10,000 - $25,000

Global NY Grant Fund

Statewide, NY
Closes: Rolling
Empire State DevelopmentSmall Business

Award Amount

$5,000 - $25,000

NYS Business Seed Funding

Statewide, NY
Closes: Rolling
Enterprise FloridaSmall Business

Award Amount

$5,000 - $5,000

Florida Export Marketing Plan

Statewide, FL
Closes: Rolling
Illinois DCEOSmall Business

Award Amount

$5,000 - $150,000

Illinois Back to Business (B2B)

Statewide, IL
Closes: Rolling
Illinois DCEOSmall Business

Award Amount

$100,000 - $500,000

Advantage Illinois (SSBCI)

Statewide, IL
Closes: Rolling
PA DCEDSmall Business

Award Amount

$2,000 - $10,000

Global Access Program (GAP)

Statewide, PA
Closes: Rolling
Economic Development AdministrationSmall Business

Award Amount

$600,000 - $5,000,000

EDA Public Works Program

National, US
Closes: Rolling
Economic Development AdministrationSmall Business

Award Amount

$150,000 - $2,500,000

EDA Economic Adjustment Assistance

National, US
Closes: Rolling
Small Business AdministrationSmall Business

Award Amount

$75,000 - $150,000

SBA Growth Accelerator Fund Competition

National, US
Closes: Varies
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA HUBZone Program

National, US
Closes: Rolling
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA 8(a) Business Development Program

National, US
Closes: Rolling
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA Women-Owned Small Business Contracting

National, US
Closes: Rolling
Governor's Office of Business and Economic DevelopmentSmall Business

Award Amount

$20,000 - $5,000,000

California Competes Tax Credit

Statewide, CA
Closes: Varies
California Infrastructure and Economic Development BankSmall Business

Award Amount

$50,000 - $1,000,000

California IBank Small Business Loan Guarantee

Statewide, CA
Closes: Rolling
Texas Workforce CommissionSmall Business

Award Amount

$2,000 - $500,000

Texas Skills Development Fund

Statewide, TX
Closes: Rolling
Enterprise FloridaSmall Business

Award Amount

$3,000 - $6,000

Florida Qualified Target Industry Tax Refund

Statewide, FL
Closes: Rolling
Illinois DCEOSmall Business

Award Amount

$25,000 - $2,000,000

Illinois EDGE Tax Credit Program

Statewide, IL
Closes: Rolling
Illinois DCEOSmall Business

Award Amount

$10,000 - $245,000

Illinois Small Business Capital & Infrastructure Grant

Statewide, IL
Closes: Varies
Ohio Department of DevelopmentSmall Business

Award Amount

$10,000 - $1,000,000

InvestOhio Tax Credit

Statewide, OH
Closes: Rolling
JobsOhioSmall Business

Award Amount

$10,000 - $50,000

JobsOhio Small Business Grant

Statewide, OH
Closes: Rolling
Georgia Department of Community AffairsSmall Business

Award Amount

$35,000 - $250,000

OneGeorgia Authority Grants

Statewide, GA
Closes: Rolling
Georgia Department of Community AffairsSmall Business

Award Amount

$50,000 - $1,000,000

Georgia REBA (Regional Economic Business Assistance)

Statewide, GA
Closes: Rolling
NC Department of CommerceSmall Business

Award Amount

$100,000 - $5,000,000

North Carolina Job Development Investment Grant

Statewide, NC
Closes: Rolling
NC Governor's OfficeSmall Business

Award Amount

$50,000 - $1,000,000

One North Carolina Fund

Statewide, NC
Closes: Rolling
Golden LEAF FoundationSmall Business

Award Amount

$50,000 - $500,000

Golden LEAF Foundation Open Grants

Statewide, NC
Closes: Varies
Michigan Strategic Fund / MEDCSmall Business

Award Amount

$50,000 - $2,000,000

Michigan Business Development Program

Statewide, MI
Closes: Rolling
Michigan Dept. of Labor and Economic OpportunitySmall Business

Award Amount

$5,000 - $200,000

Michigan Going PRO Talent Fund

Statewide, MI
Closes: Varies
MEDC / Michigan Main Street ProgramSmall Business

Award Amount

$5,000 - $25,000

Michigan Match on Main

Statewide, MI
Closes: Varies
Washington Department of CommerceSmall Business

Award Amount

$2,000 - $10,000

Washington State Export Voucher Program

Statewide, WA
Closes: Rolling
Washington Department of CommerceSmall Business

Award Amount

$25,000 - $250,000

Washington Small Business Flex Fund

Statewide, WA
Closes: Rolling
Massachusetts Growth Capital CorporationSmall Business

Award Amount

$5,000 - $50,000

Massachusetts Biz-M-Power Crowdfunding Match

Statewide, MA
Closes: Rolling
Virginia Economic Development PartnershipSmall Business

Award Amount

$50,000 - $2,000,000

Virginia Commonwealth Opportunity Fund

Statewide, VA
Closes: Rolling
Minnesota DEEDSmall Business

Award Amount

$50,000 - $1,000,000

Minnesota Job Creation Fund

Statewide, MN
Closes: Rolling
Business OregonSmall Business

Award Amount

$50,000 - $500,000

Oregon Business Development Fund

Statewide, OR
Closes: Rolling
Maryland Department of CommerceSmall Business

Award Amount

$10,000 - $50,000

Maryland Small Business Grant Program

Statewide, MD
Closes: Varies
Hello AliceSmall Business

Award Amount

$5,000 - $25,000

Hello Alice Small Business Growth Fund

National, US
Closes: Rolling
Hello Alice / AllstateSmall Business

Award Amount

$20,000 - $20,000

Allstate Main Street Grants (Hello Alice)

National, US
Closes: Rolling
Hello Alice / H&R BlockSmall Business

Award Amount

$10,000 - $50,000

Fund Her Future Grant (H&R Block)

National, US
Closes: Varies
KivaSmall Business

Award Amount

$1,000 - $15,000

Kiva 0% Interest Microloans

National, US
Closes: Rolling
FedExSmall Business

Award Amount

$10,000 - $10,000

FedEx Amplify Growth Lab

National, US
Closes: Varies
FedExSmall Business

Award Amount

$10,000 - $10,000

FedEx Boost Camp

National, US
Closes: Varies
Amazon BusinessSmall Business

Award Amount

$15,000 - $25,000

Amazon Business Small Business Grant

National, US
Closes: Varies
ComcastSmall Business

Award Amount

$5,000 - $10,000

Comcast RISE

National, US
Closes: Varies
Intuit QuickBooksSmall Business

Award Amount

$20,000 - $20,000

Intuit QuickBooks Small Business Hero

National, US
Closes: 2026-05-15
Ladies Who LaunchSmall Business

Award Amount

$10,000 - $10,000

Ladies Who Launch Program

National, US
Closes: Varies
Freed FellowshipSmall Business

Award Amount

$500 - $2,500

Freed Fellowship Grant

National, US
Closes: Monthly
eBaySmall Business

Award Amount

$10,000 - $10,000

eBay Up & Running Grants

National, US
Closes: Varies
NavSmall Business

Award Amount

$5,000 - $10,000

Nav Small Business Grants

National, US
Closes: Quarterly
CartierSmall Business

Award Amount

$30,000 - $100,000

Cartier Women's Initiative (2027 Cycle)

National, US
Closes: 2026-06-16
Boundless Futures FoundationSmall Business

Award Amount

$10,000 - $50,000

EmpowHer Grant

National, US
Closes: 2026-06-01
Halstead BeadSmall Business

Award Amount

$7,500 - $7,500

Halstead Grant for Jewelry Designers

National, US
Closes: 2026-05-01
Girlboss FoundationSmall Business

Award Amount

$15,000 - $15,000

Girlboss Foundation Grant

National, US
Closes: Varies
Spanx by Sara Blakely FoundationSmall Business

Award Amount

$5,000 - $5,000

Red Backpack Fund (Spanx Foundation)

National, US
Closes: Monthly
Tory Burch FoundationSmall Business

Award Amount

$5,000 - $5,000

Tory Burch Foundation Fellows

National, US
Closes: Varies
National Association of Women Business Owners / MastercardSmall Business

Award Amount

$10,000 - $10,000

NAWBO / Mastercard Small Business Grants

National, US
Closes: Varies
Second Service FoundationSmall Business

Award Amount

$2,000 - $5,000

Second Service Foundation Veteran Awards

National, US
Closes: Monthly
U.S. Chamber of Commerce FoundationSmall Business

Award Amount

$10,000 - $25,000

Hiring Our Heroes Small Business Grant

National, US
Closes: Varies
PenFed FoundationSmall Business

Award Amount

$5,000 - $50,000

PenFed Foundation Veteran Entrepreneur Program

National, US
Closes: Rolling
NAACPSmall Business

Award Amount

$25,000 - $25,000

NAACP Powershift Entrepreneur Grant

National, US
Closes: Varies
NAACP / L'OrealSmall Business

Award Amount

$25,000 - $25,000

NAACP x L'Oreal Beauty Industry Grants

National, US
Closes: 2026-04-23
Fearless Fund / MastercardSmall Business

Award Amount

$10,000 - $20,000

Fearless Strivers Grant (Fearless Fund + Mastercard)

National, US
Closes: Rolling
First Nations Development InstituteSmall Business

Award Amount

$1,500 - $5,000

First Nations Acorn Fund

National, US
Closes: 2026-04-29
National Black MBA AssociationSmall Business

Award Amount

$10,000 - $50,000

NBMBAA Scale-Up Pitch Challenge

National, US
Closes: Varies
National Disability Institute / Verizon / SBASmall Business

Award Amount

$5,000 - $10,000

NDI Small Business Hub (Disability Entrepreneurs)

National, US
Closes: Rolling
NAACP / Vistaprint / Boston CelticsSmall Business

Award Amount

$25,000 - $25,000

NAACP Power Forward Small Business Grant

National, US
Closes: Rolling
U.S. Hispanic Chamber of Commerce / Wells FargoSmall Business

Award Amount

$5,000 - $15,000

USHCC / Wells Fargo Hispanic Business Grants

National, US
Closes: Varies

Frequently Asked Questions

How do I apply for NIH SBIR funding?

Start at seed.nih.gov to identify the right NIH institute for your technology. Submit through Grants.gov using the standard SBIR/STTR application forms. Receipt dates are typically in April, August, and December. You will need a strong research plan, preliminary data, and a principal investigator primarily employed by your company.

Can a digital health startup get SBIR grants?

Yes. NIH, NSF, and DOD all fund digital health innovations including telehealth platforms, health AI, electronic health records, clinical decision support, and patient engagement tools. The key is framing your technology as addressing a significant health challenge with a clear commercialization path.

Are there grants for medical device companies?

Absolutely. NIH SBIR funds medical devices across all therapeutic areas. The NSF funds novel biomedical engineering approaches. DOD SBIR supports devices with military medical applications. State programs like Maryland TEDCO and Ohio Third Frontier also invest in medical device startups.

Do healthcare grants require FDA approval?

Not for initial funding. SBIR Phase I grants fund feasibility and early development, well before FDA submission. However, your application should demonstrate awareness of the regulatory pathway and a realistic timeline for FDA clearance or approval. Having a regulatory strategy strengthens your application significantly.

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