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Small Business Grants in Massachusetts

Massachusetts is a global leader in innovation, home to Harvard, MIT, and a dense ecosystem of research institutions, venture capital firms, and technology companies. The state's small business grant landscape is deeply connected to its strengths in biotechnology, healthcare, clean energy, robotics, financial technology, and education. While operating costs are high, the concentration of talent, capital, and support programs makes Massachusetts one of the most productive environments for grant-funded business growth.

Economic Overview

Massachusetts has approximately 690,000 small businesses employing over 1.5 million workers. The state's economy is driven by education, healthcare, biotechnology, technology, financial services, and defense. Greater Boston is one of the top three startup ecosystems in the US, attracting billions in venture capital annually. Massachusetts has the highest concentration of NIH and NSF funding per capita, creating extensive opportunities for research-based businesses.

State Grant Programs

MassDevelopment offers financing and grants for business expansion. The Massachusetts Technology Collaborative (MassTech) provides grants through the Innovation Institute. The Massachusetts Clean Energy Center (MassCEC) funds clean energy businesses. The Massachusetts Life Sciences Center offers tax incentives and grants for biotech companies. The Small Business Technical Assistance Grant Program funds organizations that help entrepreneurs. The Massachusetts SBDC has offices across the state.

How to Apply

Contact the Massachusetts SBDC and explore MassTech, MassCEC, and the Mass Life Sciences Center based on your industry. For federal research grants, MIT and Harvard's tech transfer offices and the Massachusetts Small Business Innovation Research program provide direct support. Register at SAM.gov.

Featured Opportunities17 Active

National Association for the Self-EmployedSmall Business

Award Amount

$4,000 - $4,000

NASE Growth Grant 2025

National, US
Closes: Rolling
WomensNetSmall Business

Award Amount

$10,000 - $25,000

Amber Grant for Women

National, US
Closes: Monthly
National Science FoundationTechnology

Award Amount

$275,000 - $275,000

America's Seed Fund (SBIR Phase I)

National, US
Closes: Rolling
FedExSmall Business

Award Amount

$10,000 - $10,000

FedEx Entrepreneur Fund (Boost Camp)

National, US
Closes: 2025-11-21
USDAAgriculture

Award Amount

$10,000 - $500,000

Rural Business Development Grants

National, US
Closes: Varies
American ExpressSmall Business

Award Amount

$5,000 - $5,000

American Express Backing Small Business

National, US
Closes: 2025-04-07
SkipSmall Business

Award Amount

$1,000 - $1,000

Skip Monthly Business Grants

National, US
Closes: Monthly
IFundWomenSmall Business

Award Amount

$5,000 - $5,000

IFundWomen Universal Grant

National, US
Closes: Rolling
VerizonSmall Business

Award Amount

$10,000 - $10,000

Verizon Small Business Digital Ready

National, US
Closes: Rolling
PayPal / VenmoSmall Business

Award Amount

$10,000 - $10,000

Venmo Small Business Grant

National, US
Closes: Varies
LegalZoom / NBASmall Business

Award Amount

$10,000 - $10,000

LegalZoom Fast Break for Small Business

National, US
Closes: 2025-09-13
CartierSmall Business

Award Amount

$30,000 - $100,000

Cartier Women's Initiative

National, US
Closes: 2025-06-30
Boundless Futures FoundationSmall Business

Award Amount

$50,000 - $50,000

EmpowHer Grant

National, US
Closes: 2026-01-30
American ExpressSmall Business

Award Amount

$20,000 - $20,000

Amex Shop Small Grants

National, US
Closes: 2026-01-23
IntuitSmall Business

Award Amount

$20,000 - $20,000

Intuit Small Business Hero

National, US
Closes: 2026-02-14
SkipSmall Business

Award Amount

$10,000 - $10,000

Skip's $10k Kickoff Grant

National, US
Closes: 2026-01-31
BrevaSmall Business

Award Amount

$5,000 - $5,000

Breva Thrive Grant

National, US
Closes: 2026-01-31

Frequently Asked Questions

What grants are available for Massachusetts startups?

Massachusetts offers MassTech Innovation Institute grants, MassCEC clean energy grants, Mass Life Sciences Center incentives, MassDevelopment financing, and is one of the best states for accessing federal SBIR/STTR funding.

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