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Small Business Grants in South Carolina

South Carolina has positioned itself as one of the most competitive states in the Southeast for business growth. With major automotive and aerospace manufacturing, a booming tourism industry along the coast, and growing technology sectors in Charleston and Greenville, the state offers diverse opportunities for small business grant funding.

Economic Overview

South Carolina has approximately 430,000 small businesses employing over 760,000 workers. The economy has been transformed by major investments in automotive (BMW, Volvo, Mercedes-Benz vans), aerospace (Boeing), and advanced manufacturing. Charleston has emerged as a significant tech hub. Tourism along the coast generates billions in revenue. The state's cost of living and business operating costs are among the lowest in the Southeast.

State Grant Programs

The SC Department of Commerce offers the Closing Fund for business recruitment, workforce training through readySC, and various tax incentives. The SC Launch program provides funding for innovative startups. The SC SBDC has offices across the state. The SC Research Authority (SCRA) supports technology companies. Charleston Digital Corridor and Greenville's NEXT Innovation Center provide local startup support.

How to Apply

Contact the SC SBDC and visit the SC Department of Commerce website. Tech startups should connect with SC Launch and SCRA. readySC provides customized, free workforce training. In Charleston, the Digital Corridor is a key resource. Register at SAM.gov for federal grants.

Featured Opportunities63 Active

National Association for the Self-EmployedSmall Business

Award Amount

$4,000 - $4,000

NASE Growth Grant

National, US
Closes: Rolling
WomensNetSmall Business

Award Amount

$10,000 - $50,000

Amber Grant for Women

National, US
Closes: Monthly
National Science FoundationTechnology

Award Amount

$275,000 - $305,000

NSF SBIR Phase I (America's Seed Fund)

National, US
Closes: Rolling
USDA Rural DevelopmentAgriculture

Award Amount

$10,000 - $500,000

USDA Rural Business Development Grants

National, US
Closes: Rolling
SkipSmall Business

Award Amount

$1,000 - $10,000

Skip Monthly Business Grants

National, US
Closes: Monthly
IFundWomenSmall Business

Award Amount

$5,000 - $25,000

IFundWomen Universal Grant Application

National, US
Closes: Rolling
VerizonSmall Business

Award Amount

$10,000 - $10,000

Verizon Small Business Digital Ready

National, US
Closes: Rolling
PayPal / VenmoSmall Business

Award Amount

$10,000 - $10,000

Venmo Small Business Grant

National, US
Closes: Varies
Department of DefenseTechnology

Award Amount

$50,000 - $275,000

DOD SBIR Phase I

National, US
Closes: Rolling
National Institutes of HealthHealthcare

Award Amount

$150,000 - $293,297

NIH SBIR/STTR Phase I

National, US
Closes: Varies
Department of EnergyTechnology

Award Amount

$50,000 - $200,000

DOE SBIR/STTR Phase I

National, US
Closes: Varies
NASATechnology

Award Amount

$150,000 - $750,000

NASA SBIR/STTR

National, US
Closes: Varies
USDA NIFAAgriculture

Award Amount

$50,000 - $150,000

USDA SBIR Phase I

National, US
Closes: Varies
Environmental Protection AgencyTechnology

Award Amount

$50,000 - $100,000

EPA SBIR Phase I

National, US
Closes: Varies
USDA Rural DevelopmentAgriculture

Award Amount

$75,000 - $750,000

USDA Value-Added Producer Grant

National, US
Closes: 2026-04-22
USDA Rural DevelopmentAgriculture

Award Amount

$2,500 - $1,000,000

USDA Rural Energy for America (REAP)

National, US
Closes: Rolling
Economic Development AdministrationSmall Business

Award Amount

$600,000 - $5,000,000

EDA Public Works Program

National, US
Closes: Rolling
Economic Development AdministrationSmall Business

Award Amount

$150,000 - $2,500,000

EDA Economic Adjustment Assistance

National, US
Closes: Rolling
Economic Development AdministrationTechnology

Award Amount

$250,000 - $2,000,000

EDA Build to Scale (Venture Challenge)

National, US
Closes: Varies
Small Business AdministrationSmall Business

Award Amount

$75,000 - $150,000

SBA Growth Accelerator Fund Competition

National, US
Closes: Varies
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA HUBZone Program

National, US
Closes: Rolling
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA 8(a) Business Development Program

National, US
Closes: Rolling
Small Business AdministrationSmall Business

Award Amount

$50,000 - $4,500,000

SBA Women-Owned Small Business Contracting

National, US
Closes: Rolling
Hello AliceSmall Business

Award Amount

$5,000 - $25,000

Hello Alice Small Business Growth Fund

National, US
Closes: Rolling
Hello Alice / AllstateSmall Business

Award Amount

$20,000 - $20,000

Allstate Main Street Grants (Hello Alice)

National, US
Closes: Rolling
Hello Alice / H&R BlockSmall Business

Award Amount

$10,000 - $50,000

Fund Her Future Grant (H&R Block)

National, US
Closes: Varies
KivaSmall Business

Award Amount

$1,000 - $15,000

Kiva 0% Interest Microloans

National, US
Closes: Rolling
FedExSmall Business

Award Amount

$10,000 - $10,000

FedEx Amplify Growth Lab

National, US
Closes: Varies
FedExSmall Business

Award Amount

$10,000 - $10,000

FedEx Boost Camp

National, US
Closes: Varies
Amazon BusinessSmall Business

Award Amount

$15,000 - $25,000

Amazon Business Small Business Grant

National, US
Closes: Varies
GoogleTechnology

Award Amount

$2,000 - $350,000

Google for Startups Cloud Program

National, US
Closes: Rolling
VisaTechnology

Award Amount

$20,000 - $100,000

Visa Everywhere Initiative

National, US
Closes: Varies
ComcastSmall Business

Award Amount

$5,000 - $10,000

Comcast RISE

National, US
Closes: Varies
Intuit QuickBooksSmall Business

Award Amount

$20,000 - $20,000

Intuit QuickBooks Small Business Hero

National, US
Closes: 2026-05-15
Ladies Who LaunchSmall Business

Award Amount

$10,000 - $10,000

Ladies Who Launch Program

National, US
Closes: Varies
Freed FellowshipSmall Business

Award Amount

$500 - $2,500

Freed Fellowship Grant

National, US
Closes: Monthly
eBaySmall Business

Award Amount

$10,000 - $10,000

eBay Up & Running Grants

National, US
Closes: Varies
NavSmall Business

Award Amount

$5,000 - $10,000

Nav Small Business Grants

National, US
Closes: Quarterly
MassChallengeTechnology

Award Amount

$25,000 - $100,000

MassChallenge Accelerator (Equity-Free)

National, US
Closes: Varies
Southern Smoke FoundationRestaurant

Award Amount

$1,000 - $5,000

Southern Smoke Emergency Relief Fund

National, US
Closes: Rolling
CartierSmall Business

Award Amount

$30,000 - $100,000

Cartier Women's Initiative (2027 Cycle)

National, US
Closes: 2026-06-16
Boundless Futures FoundationSmall Business

Award Amount

$10,000 - $50,000

EmpowHer Grant

National, US
Closes: 2026-06-01
Halstead BeadSmall Business

Award Amount

$7,500 - $7,500

Halstead Grant for Jewelry Designers

National, US
Closes: 2026-05-01
Girlboss FoundationSmall Business

Award Amount

$15,000 - $15,000

Girlboss Foundation Grant

National, US
Closes: Varies
Spanx by Sara Blakely FoundationSmall Business

Award Amount

$5,000 - $5,000

Red Backpack Fund (Spanx Foundation)

National, US
Closes: Monthly
Tory Burch FoundationSmall Business

Award Amount

$5,000 - $5,000

Tory Burch Foundation Fellows

National, US
Closes: Varies
National Association of Women Business Owners / MastercardSmall Business

Award Amount

$10,000 - $10,000

NAWBO / Mastercard Small Business Grants

National, US
Closes: Varies
Second Service FoundationSmall Business

Award Amount

$2,000 - $5,000

Second Service Foundation Veteran Awards

National, US
Closes: Monthly
U.S. Chamber of Commerce FoundationSmall Business

Award Amount

$10,000 - $25,000

Hiring Our Heroes Small Business Grant

National, US
Closes: Varies
PenFed FoundationSmall Business

Award Amount

$5,000 - $50,000

PenFed Foundation Veteran Entrepreneur Program

National, US
Closes: Rolling
NAACPSmall Business

Award Amount

$25,000 - $25,000

NAACP Powershift Entrepreneur Grant

National, US
Closes: Varies
NAACP / L'OrealSmall Business

Award Amount

$25,000 - $25,000

NAACP x L'Oreal Beauty Industry Grants

National, US
Closes: 2026-04-23
Fearless Fund / MastercardSmall Business

Award Amount

$10,000 - $20,000

Fearless Strivers Grant (Fearless Fund + Mastercard)

National, US
Closes: Rolling
First Nations Development InstituteSmall Business

Award Amount

$1,500 - $5,000

First Nations Acorn Fund

National, US
Closes: 2026-04-29
First Nations Development InstituteAgriculture

Award Amount

$10,000 - $40,000

First Nations Native Food Sovereignty Grant

National, US
Closes: Varies
National Black MBA AssociationSmall Business

Award Amount

$10,000 - $50,000

NBMBAA Scale-Up Pitch Challenge

National, US
Closes: Varies
SoGal FoundationTechnology

Award Amount

$5,000 - $10,000

SoGal Foundation Black Founder Grant

National, US
Closes: Rolling
DigitalUndivided / JPMorgan ChaseTechnology

Award Amount

$5,000 - $5,000

DigitalUndivided Breakthrough Program

National, US
Closes: Varies
National Disability Institute / Verizon / SBASmall Business

Award Amount

$5,000 - $10,000

NDI Small Business Hub (Disability Entrepreneurs)

National, US
Closes: Rolling
NAACP / BACARDIRestaurant

Award Amount

$5,000 - $25,000

NAACP x BACARDI Backing the B.A.R.

National, US
Closes: Varies
NAACP / Vistaprint / Boston CelticsSmall Business

Award Amount

$25,000 - $25,000

NAACP Power Forward Small Business Grant

National, US
Closes: Rolling
MetaTechnology

Award Amount

$25,000 - $200,000

Meta AI Glasses Impact Grants

National, US
Closes: Varies
U.S. Hispanic Chamber of Commerce / Wells FargoSmall Business

Award Amount

$5,000 - $15,000

USHCC / Wells Fargo Hispanic Business Grants

National, US
Closes: Varies

Frequently Asked Questions

What grants does South Carolina offer?

SC offers SC Launch startup funding, readySC workforce training, SCRA technology support, tax incentives through the Department of Commerce, and federal SBIR/STTR and USDA programs.

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